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Geistlich Fibro-Gide®

 

Geistlich Fibro-Gide® is a porcine, porous, resorbable and volume-stable collagen matrix, specifically designed for soft-tissue regeneration.1,4,10 The collagen matrix is made of reconstituted collagen and undergoes smart chemically cross-linking to improve its volume stability while maintaining a good biocompatibility.1-3,4-10 The porous network of Geistlich Fibro-Gide® supports angiogenesis, formation of new connective tissue and stability of the collagen network in submerged healing.2,3 In vivo animal models have shown good integration of Geistlich Fibro-Gide® into the surrounding soft-tissue while maintaining stability.4

Geistlich Fibro-Gide® is the alternative to autogenous connective tissue grafts (CTG), which are considered as the gold standard in regenerative soft-tissue procedures.3,5,6 With Geistlich Fibro-Gide® additional harvest site is avoided, patient morbidity is reduced.3,7-8

 

Inspired by Nature, engineered by Geistlich

The collagen expertise of Geistlich has led to a tailor-made product meeting the clinical needs and providing therapeutic solutions in oral soft-tissue regeneration. More than 1,000 prototypes were developed and tested in order to get a product like Geistlich Fibro-Gide®.10

Product availability may vary from country to country.

 

References 

  1. Mathes SH. Et al. Biotechnol Bioeng. 2010 Dec 15;107(6):1029-39. (preclinical study). 
  2. Thoma DS. et al. Clin Oral Implants Res. 2015 Mar; 26(3): 263–70. (preclinical study)
  3. Thoma DS. et al. J Clin Periodontol. 2016 Oct; 43(10): 874–85. (clinical study)
  4. Thoma DS. et al. Clin Oral Implants Res. 2012 Dec; 23(12): 1333–9. (preclinical study)
  5. Thoma DS. et al. Clin Oral Implants Res. 2009 Sep; 20 Suppl 4: 146–65. (systematic review based on clinical studies)
  6. Thoma DS. et al. J Clin Periodontol. 2014 Apr; 41 Suppl 15: S77–91.  (systematic review based on clinical studies)
  7. Del Pizzo M. et al. J Clin Periodontol. 2002 Sep; 29(9): 848–54. (clinical study)
  8. Soileau KM. & Brannon RB. J Periodontol. 2006 Jul; 77(7): 1267–73. (clinical study)
  9. Zeltner M. et al. J Clin Periodontol. 2017 Apr; 44(4): 446–453. (clinical study)
  10. Data on file. Geistlich Pharma AG, Wolhusen, Switzerland.
Verena Vermeulen
Group Lead Clinical Marketing