Periodontal treatment

Periodontal disease is characterised by the destruction of periodontal tissue. If non-surgical, Phase I treatment such as patient education, plaque control, scaling and root planing fails, further surgical solutions are required.

The use of biomaterials for guided tissue regeneration (GTR) is more effective than open flap debridement alone in resolving periodontal defects1. During this procedure the defect is filled with the natural bone substitute Geistlich Bio-Oss® (Collagen) and covered with the collagen membrane Geistlich Bio-Gide® (Perio).

Natural bone substitute should:

  • Fill the osseous defect and reduce pocket depth
  • Generate increased levels of clinical attachment
  • Stimulate regeneration and preservation of patient’s own bone and periodontal ligament

Collagen barrier membranes should:

  • Stabilize the grafted area and protecting bone particles from dislocation5
  • Prevent soft-tissue ingrowth to the defect6-10
  • Serve as a framework for bone cells and blood vessels6,8


Higher attachment gain with Geistlich Bio-Oss® and Geistlich Bio-Gide® Perio

The use of a Geistlich bone substitute material together with native collagen membrane Geistlich Bio-Gide® Perio produces significantly better results than open flap debridement alone. Five-year data show higher clinical attachment level gains and greater pocket depth reduction1.



  1. Sculean A et al., J Clin Periodontol. 2007 Jan;34(1):72-77 (Clinical study). 37
  2. Newman MG, et al., Caranza's Clinical Periodontology. Elsevier (Book).
  3. Lindhe J, et al., Clinical Periodontology and Implant Dentistry. Blackwell Munksgaard (Book).
  4. Rateitschak EM, Wolf HF, Farbatlanten der Zahnmedizin. Band 1: Parodontologie. Thieme (Book)
  5. Perelman-Karmon M et al. Int J Periodontics Restorative Dent. 2012 Aug;32(4):459-65. (Clinical study)
  6. Schwarz F et al. Clin. Oral Implants Res. 2006;17(4):403-409. (Pre-clinical study)
  7. Tal H et al. Clin Oral Implants Res. 2008; 19(3) : 295-302. (Clinical study)
  8. Rothamel D et al. Clin. Oral Implants Res. 2005; 16(3): 369-378. (Pre-clinical study)
  9. Zitzmann NU et al. Int J Oral Maxillofac Implants.12, 1997;844-852. (Clinical study)
  10. Rothamel D et al. Clin. Oral Implants Res. 2004;15:443-449. (Pre-clinical study)
Verena Vermeulen
Senior Scientific Communication Manager