Geistlich Bio-Gide®

Geistlich Bio-Gide® is a collagen membrane for reliable bone regeneration and optimal tissue integration.1-3. The natural collagen structure of Geistlich Bio-Gide® permits prompt and homogeneous vascularization and so brings about optimal tissue integration and wound stabilization.5 The smooth side of Geistlich Bio-Gide® prevents soft tissue from growing into the defect and serves as a scaffold for the attachment of fibroblasts. 1,4-7 The rough, open-pored layer side of Geistlich Bio-Gide® serves as a framework for bone cells and blood vessels. 1,9. Geistlich Bio-Gide® is used in combination with a bone substitute such as Geistlich Bio-Oss® or Geistlich Bio-Oss® Collagen.

 

Geistlich Bio-Gide® is naturally resorbable and does not have to be removed in a second surgery. As it simplifies the surgery technique, and thanks to its optimal wound healing properties4,6, Geistlich Bio-Gide® has fundamentally changed dental bone regeneration.

“The Geistlich Bio-Gide® membrane has, for 20 years, proven itself to be reliable and is characterized by easy clinical handling and a low complication rate.”
Prof. Daniel Buser, Berne, Switzerland

 

Leading clinicians rely on Geistlich Bio-Gide® for:

  • Optimal tissue integration and wound stabilization1,5,9
  • High therapy safety even in case of dehiscence 4,8
  • 11% more new bone formation with Geistlich Bio-Oss® and Geistlich Bio-Gide® vs Geistlich Bio-Oss® alone10
  • Simplified surgery without removal of the membrane
  • Aesthetically stable results after 5-9 years11
  • Long-term data over 12 to 14 years show predictable results of bone augmentations with Geistlich Bio-Oss® and Geistlich Bio-Gide®12

In the 1990s, Dr. Peter Geistlich was the first to develop a natural collagen membrane that optimally meets the requirements for regenerative dentistry. Meanwhile Geistlich Bio-Gide® is a collagen membrane1,2, validated by over 20 years of successful use in more than two million patients and documented in more than 250 scientific publications13-15.

 

References:

  1. Schwarz F et al. Clin. Oral Implants Res. 2006;17(4):403-409. (Pre-clinical study)
  2. Rothamel D et al. Clin. Oral Implants Res. 2005; 16(3): 369-378. (Pre-clinical study)
  3. Schwarz F et al. Clin Oral Implants Res. 2014 Sept;25(9):1010-5. (Clinical study)
  4. Tal H et al. Clin Oral Implants Res. 2008; 19(3) : 295-302. (Clinical study)
  5. Rothamel D et al. Clin. Oral Implants Res. 2005; 16(3): 369-378. (Pre-clinical study
  6. Zitzmann NU et al. Int J Oral Maxillofac Implants.12, 1997;844-852. (Clinical study)
  7. Rothamel D et al. Clin. Oral Implants Res. 2004;15:443-449. (Pre-clinical study)
  8. Becker J et al. Clin Oral Implants Res. 2009; 20(7):742-749. (Clinical study)
  9. Schwarz F et al. Clin. Oral Implants Res. 2008;19(4): 402-415. (Pre-clinical study
  10. Perelman-Karmon M et al. Int J Periodontics Restorative Dent. 2012 Aug;32(4):459-65. (Clinical study)
  11. Buser D et al. J Periodontol 2013; 84(11): 1517-27. (Clinical study).
  12. Jung RE et al. Clin. Oral Implants Res. 2013 Oct;24(10):1065-73. (Clinical study)
  13. Pubmed September 2016. Search Term: Bio-Gide.
  14. iData Research Inc., US Dental Bone Graft Substitutes and other Biomaterials Market, 2015.
  15. iData Inc., European Dental Bone Graft Substitutes and other Biomaterials Market, 2015

 

Verena Vermeulen
Senior Scientific Communication Manager