Geistlich Bio-Gide^®

Geistlich Bio-Gide^® is a collagen membrane for reliable bone regeneration and optimal tissue integration.^1-3. The natural collagen structure of Geistlich Bio-Gide® permits prompt and homogeneous vascularization and so brings about optimal tissue integration and wound stabilization.⁵ The smooth side of Geistlich Bio-Gide® prevents soft tissue from growing into the defect and serves as a scaffold for the attachment of fibroblasts. ^1,4-7 The rough, open-pored layer side of Geistlich Bio-Gide® serves as a framework for bone cells and blood vessels. ^1,9. Geistlich Bio-Gide^® is used in combination with a bone substitute such as Geistlich Bio-Oss^® or Geistlich Bio-Oss^® Collagen.

Geistlich Bio-Gide^® is naturally resorbable and does not have to be removed in a second surgery. As it simplifies the surgery technique, and thanks to its optimal wound healing properties^4,6, Geistlich Bio-Gide^® has fundamentally changed dental bone regeneration.

Leading clinicians rely on Geistlich Bio-Gide^® for:

• Optimal tissue integration and wound stabilization^1,5,9
• High therapy safety even in case of dehiscence ^4,8
• 11% more new bone formation with Geistlich Bio-Oss^® and Geistlich Bio-Gide^® vs Geistlich Bio-Oss^® alone¹⁰
• Simplified surgery without removal of the membrane
• Aesthetically stable results after 5-9 years¹¹
• Long-term data over 12 to 14 years show predictable results of bone augmentations with Geistlich Bio-Oss^® and Geistlich Bio-Gide^®12

In the 1990s, Dr. Peter Geistlich was the first to develop a natural collagen membrane that optimally meets the requirements for regenerative dentistry. Meanwhile Geistlich Bio-Gide^® is a collagen membrane^1,2, validated by over 20 years of successful use in more than two million patients and documented in more than 250 scientific publications^13-15.

References:

1. Schwarz F et al. Clin. Oral Implants Res. 2006;17(4):403-409. (Pre-clinical study)
2. Rothamel D et al. Clin. Oral Implants Res. 2005; 16(3): 369-378. (Pre-clinical study)
3. Schwarz F et al. Clin Oral Implants Res. 2014 Sept;25(9):1010-5. (Clinical study)
4. Tal H et al. Clin Oral Implants Res. 2008; 19(3) : 295-302. (Clinical study)
5. Rothamel D et al. Clin. Oral Implants Res. 2005; 16(3): 369-378. (Pre-clinical study
6. Zitzmann NU et al. Int J Oral Maxillofac Implants.12, 1997;844-852. (Clinical study)
7. Rothamel D et al. Clin. Oral Implants Res. 2004;15:443-449. (Pre-clinical study)
8. Becker J et al. Clin Oral Implants Res. 2009; 20(7):742-749. (Clinical study)
9. Schwarz F et al. Clin. Oral Implants Res. 2008;19(4): 402-415. (Pre-clinical study
10. Perelman-Karmon M et al. Int J Periodontics Restorative Dent. 2012 Aug;32(4):459-65. (Clinical study)
11. Buser D et al. J Periodontol 2013; 84(11): 1517-27. (Clinical study).
12. Jung RE et al. Clin. Oral Implants Res. 2013 Oct;24(10):1065-73. (Clinical study)
13. Pubmed September 2016. Search Term: Bio-Gide.
14. iData Research Inc., US Dental Bone Graft Substitutes and other Biomaterials Market, 2015.
15. iData Inc., European Dental Bone Graft Substitutes and other Biomaterials Market, 2015