Orthoss® Collagen

Orthoss® Collagen is a highly purified natural bone mineral combined with native collagen, designed for orthopaedic bone regeneration. Granules of cancellous bone mineral provide an optimal osteoconductive matrix for bone regeneration. Natural collagen delivers superior handling characteristics to the composite


While the collagen part of the material is resorbed within weeks, the slow resorption rate of the mineral scaffold provides a protective environment and volume maintenance during bone ingrowth.4,5

The large inner surface also results in exceptional osteoconductivity and osseointegration. The biofunctionality of the natural material further enhances bone ingrowth and vascularisation.1,2,6,7


  1. Rohner, D. et al. (2013). Int J Oral Maxillofac Surg. 42(5): 585-91.
  2. Trevisiol, L. et al. (2012). J Craniofac Surg. 23(5): 1343-8
  3. Data on file at Geistlich Pharma AG, Wolhusen, Switzerland.
  4. Araujo, MG. et al. (2009). Clin Oral Impl Res. 21: 55-64.
  5. Schlegel, KA et al. (2003). Int J Oral Maxillofac Implants. 18(1): 53-8.
  6. Schlickewei, W. et al. (1991). Hefte zur Unfallkunde,.216: 59-69.
  7. Bereiter, H. et al. (1991). Hefte zur Unfallkunde. 216: 117-126.




Dr. Sanja Saftic
International Product Manager