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Geistlich Mucograft® is a unique 3D collagen matrix designed for oral soft-tissue regeneration. It provides a user-friendly alternative to autogenous soft-tissue grafts.

Geistlich Mucograft®

Geistlich Mucograft® is a unique 3D collagen matrix designed specifically for soft-tissue regeneration in the oral cavity1. It is indicated for gaining keratinised tissue2,3,4  and for recession coverage5,6.

Geistlich Mucograft® provides an alternative to autogenous soft-tissue grafts2,4,5,6. Painful harvesting of tissue is avoided, benefiting patients and clinicians alike.

 

Leading clinicaians rely on Geistlich Mucograft®:

  • No harvest-site morbidity2,3,5-7.
  • Less pain compared with autogenous grafts2,4.
  • Reduced surgical chair-time compared with autogenous grafts2-6.
  • Natural soft-tissue colour and texture match5,8,9.
  • Early vascularisation and good soft-tissue ingrowth10,11.
  • Excellent wound healing, also in open situations2.
  • Easy handling2 and application in a dry state.

Geistlich Mucograft® consists of two structures: the compact structure provides stability while allowing open healing; the spongy structure supports blood clot stabilisation and ingrowth of soft-tissue cells.

 

References:

  1. Biocompatibility according to ISO 10993-1:2001. Data on file, Geistlich Pharma AG, Wolhusen, Switzerland.
  2. Sanz M, et al.: J Clin Periodontol 2009; 36(10): 868-76.
  3. Konter U, et al.: Deutsche Zahnärztliche Zeitschrift 2010; 65: 723-30.
  4. Lorenzo R, et al.: Clin Oral Impl Res 2012; 23(3): 316-24.
  5. McGuire MK & Scheyer ET: J Periodontol 2010; 81(8): 1108-17.
  6. Cardaropoli D, et al.: J Periodontol 2012; 83(3): 321-28.
  7. Herford AS, et al.: J Oral Maxillofac Surg 2010; 68(7): 1463-70.
  8. Thoma, D, et al.: J Clin Periodontol 2012; 39(2): 157-65.
  9. Nevins M, et al.: Int J Periodontics Restorative Dent 2011; 31(4): 367-73.
  10. Ghanaati S, et al.: Biomed Mater. 2011 Feb; 6(1): 015010.
  11. Rocchietta I, et al.: Int J Periodontics Restorative Dent 32(1): e34-40.

* Mucograft® (prototype) exhibited highly similar physical, mechanical and biological properties to the final product Geistlich Mucograft® differing only in the porcine collagen source used.

 

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Verena Vermeulen
Scientific Communication Manager